Donor DNA processing is blocked by a mutation in the com101A locus of Haemophilus influenzae

Author:

Larson T G1,Goodgal S H1

Affiliation:

1. Graduate Group in Biochemistry, University of Pennsylvania School of Medicine, Philadelphia 19104.

Abstract

Evidence is presented indicating that a donor DNA processing step of the Haemophilus influenzae transformation pathway is blocked in the Com-101 mutant. Additional data are presented suggesting that, as in the Rec-2 strain, the donor DNA remains associated with the H. influenzae envelope.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference16 articles.

1. Directional transport and integration of donor DNA in Haemophilus influenzae transformation;Barany F.;Proc. Natl. Acad. Sci. USA,1983

2. Reexamination of phenotypic defects in rec-J and rec-2 mutants of Haemophilus influenzae Rd;Barouki R.;J. Bacteriol.,1985

3. Thymine and thymidine uptake by Haemophilus influenzae and the labeling of deoxyribonucleic acid;Carmody J. M.;J. Bacteriol.,1970

4. Defined nongrowth media for stage II development of competence in Haemophilus influenzae;Herriott R. M.;J. Bacteriol.,1970

5. Kooistra J. and G. Venema. 1971. Effect of temperature on the fate of donor DNA in transformation of Haemophilus influen zae p. 408-417. In L. Ledoux (ed.) Informative Molecules in Biological Systems. Elsevier New York.

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