OXA-181-Producing Extraintestinal Pathogenic Escherichia coli Sequence Type 410 Isolated from a Dog in Portugal-Reference-Cited by-同舟云学术

OXA-181-Producing Extraintestinal Pathogenic Escherichia coli Sequence Type 410 Isolated from a Dog in Portugal

Published:2020-03-24 Issue:4 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Brilhante Michael¹²,Menezes Juliana³,Belas Adriana³,Feudi Claudia⁴,Schwarz Stefan⁴^ORCID,Pomba Constança³^ORCID,Perreten Vincent¹^ORCID

Affiliation:

1. Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

2. Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland

3. Centre for Interdisciplinary Research in Animal Health (CIISA), Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal

4. Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany

Abstract

Two multidrug-resistant and carbapenemase-producing Escherichia coli clones of sequence type 410 were isolated from fecal samples of a dog with skin infection on admission to an animal hospital in Portugal and 1 month after discharge. Whole-genome sequencing revealed a 126,409-bp Col156/IncFIA/IncFII multidrug resistance plasmid and a 51,479-bp IncX3 bla OXA-181 -containing plasmid. The chromosome and plasmids carried virulence genes characteristic for uropathogenic E. coli , indicating that dogs may carry multidrug-resistant E. coli isolates related to those causing urinary tract infections in humans.

Funder

Bundesministerium für Bildung und Forschung

MEC | Fundação para a Ciência e a Tecnologia

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02298-19

Reference28 articles.

1. Carbapenem-resistant Enterobacteriaceae in wildlife, food-producing, and companion animals: a systematic review