PopB-PcrV Interactions Are Essential for Pore Formation in the Pseudomonas aeruginosa Type III Secretion System Translocon-Reference-Cited by-同舟云学术

PopB-PcrV Interactions Are Essential for Pore Formation in the Pseudomonas aeruginosa Type III Secretion System Translocon

Published:2022-10-26 Issue:5 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Kundracik Emma¹^ORCID,Trichka Josephine²³^ORCID,Díaz Aponte José¹³⁴,Roistacher Alicia¹^ORCID,Rietsch Arne¹^ORCID

Affiliation:

1. Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, USA

2. Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

3. Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA

4. Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, USA

Abstract

Type III secretion systems are integral to the pathogenesis of many Gram-negative bacterial pathogens. A hallmark of these secretion systems is that they deliver effector proteins vectorially into the targeted host cell via a translocation pore.

Funder

HHS | NIH | National Eye Institute

HHS | NIH | National Institute of General Medical Sciences

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02381-22

Reference59 articles.

1. Pseudomonas aeruginosa: breaking down barriers

2. On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome

3. Anti-PcrV antibody strategies against virulentPseudomonas aeruginosa

4. Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

5. CryoEM of bacterial secretion systems: A primer for microbiologists

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