Accurate Quantification of Overlapping Herpesvirus Transcripts from RNA Sequencing Data

Author:

Casco Alejandro1,Gupta Akansha1,Hayes Mitchell1,Djavadian Reza1,Ohashi Makoto1,Johannsen Eric12ORCID

Affiliation:

1. Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, USA

2. Department of Medicine, Division of Infectious Diseases, University of Wisconsin, Madison, Wisconsin, USA

Abstract

Many viruses employ extensively overlapping transcript structures. This complexity makes it difficult to quantify gene expression by using conventional methods, including RNA-seq.

Funder

HHS | NIH | National Cancer Institute

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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