Responses of the Soil Bacterial Community, Resistome, and Mobilome to a Decade of Annual Exposure to Macrolide Antibiotics-Reference-Cited by-同舟云学术

Responses of the Soil Bacterial Community, Resistome, and Mobilome to a Decade of Annual Exposure to Macrolide Antibiotics

Published:2022-04-26 Issue:8 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Brown Liam P.¹²^ORCID,Murray Roger¹,Scott Andrew¹,Tien Yuan-Ching¹,Lau Calvin Ho-Fung³,Tai Vera²,Topp Edward¹²^ORCID

Affiliation:

1. London Research and Development Centre, Agriculture and Agri-Food Canada, London, Ontario, Canada

2. Department of Biology, University of Western Ontario, London, Ontario, Canada

3. Ottawa Laboratory (Carling), Canadian Food Inspection Agency, Ottawa, Ontario, Canada

Abstract

Biosolids, produced from the treatment of sewage sludge, are rich in plant nutrients and are a valuable alternative to inorganic fertilizer when applied to agricultural soil. However, the use of biosolids in agriculture, which are frequently contaminated with pharmaceuticals, such as macrolide antibiotics, may pose a risk to human health by selecting for antibiotic resistance genes that could be transferred to plant-based food destined for human consumption.

Funder

Gouvernement du Canada | Agriculture and Agri-Food Canada

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.00316-22

Reference68 articles.

1. Negative environmental impacts of antibiotic-contaminated effluents from pharmaceutical industries

2. Promoting resistance by the emission of antibiotics from hospitals and households into effluent

3. Heavy use of prophylactic antibiotics in aquaculture: a growing problem for human and animal health and for the environment