In Vitro Activities of 35 Double Combinations of Antifungal Agents against Scedosporium apiospermum and Scedosporium prolificans-Reference-Cited by-同舟云学术

In Vitro Activities of 35 Double Combinations of Antifungal Agents against Scedosporium apiospermum and Scedosporium prolificans

Published:2008-03 Issue:3 Volume:52 Page:1136-1139
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Cuenca-Estrella Manuel¹,Alastruey-Izquierdo Ana¹,Alcazar-Fuoli Laura¹,Bernal-Martinez Leticia¹,Gomez-Lopez Alicia¹,Buitrago Maria J.¹,Mellado Emilia¹,Rodriguez-Tudela Juan L.¹

Affiliation:

1. Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, España

Abstract

ABSTRACT Activities of 35 combinations of antifungal agents against Scedosporium spp. were analyzed by a checkerboard microdilution design and the summation of fractional concentration index. An average indifferent effect was detected apart from combinations of azole agents and echinocandins against Scedosporium apiospermum . Antagonism was absent for all antifungal combinations against both species.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01160-07

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