Structural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor Receptor
Author:
Affiliation:
1. Immune Disease Institute and Department of Pathology, Harvard Medical School, 3 Blackfan Circle, Boston, Massachusetts 02115
2. Department of Biophysics and Biochemistry, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Abstract
Publisher
American Society for Microbiology
Subject
Cell Biology,Molecular Biology
Link
https://journals.asm.org/doi/pdf/10.1128/MCB.00742-10
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4. Bocharov, E. V., K. S. Mineev, P. E. Volynsky, Y. S. Ermolyuk, E. N. Tkach, A. G. Sobol, V. V. Chupin, M. P. Kirpichnikov, R. G. Efremov, and A. S. Arseniev. 2008. Spatial structure of the dimeric transmembrane domain of the growth factor receptor ErbB2 presumably corresponding to the receptor active state. J. Biol. Chem.283:6950-6956.
5. Bonneau, R., C. E. Strauss, C. A. Rohl, D. Chivian, P. Bradley, L. Malmstrom, T. Robertson, and D. Baker. 2002. De novo prediction of three-dimensional structures for major protein families. J. Mol. Biol.322:65-78.
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