Stability and Antibacterial Activity of Cefepime during Continuous Infusion-Reference-Cited by-同舟云学术

Stability and Antibacterial Activity of Cefepime during Continuous Infusion

Published:2003-06 Issue:6 Volume:47 Page:1991-1994
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Sprauten Pål F.¹²,Beringer Paul M.²,Louie Stan G.²,Synold Timothy W.³,Gill Mark A.²

Affiliation:

1. University of Oslo, Oslo, Norway

2. University of Southern California, Los Angeles

3. City of Hope, Duarte, California

Abstract

ABSTRACT The stability of cefepime during simulated continuous infusion was determined with a motorized portable infusion pump worn over a period of 24 to 36 h. Susceptibility testing on cefepime solutions over time indicates that the degradation products do not exhibit antibacterial activity. Cefepime stability at 24 h following continuous infusion was 94.3% ± 1.0%, which supports the use of continuous infusion.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.47.6.1991-1994.2003

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