Surface-Bonded Antimicrobial Activity of an Organosilicon Quaternary Ammonium Chloride

Author:

Isquith A. J.1,Abbott E. A.1,Walters P. A.1

Affiliation:

1. Biomedical Research and Development Laboratory, Dow Corning Corporation, Midland, Michigan 48640

Abstract

The hydrolysis product of 3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride exhibited antimicrobial activity against a broad range of microorganisms while chemically bonded to a variety of surfaces. The chemical was not removed from surfaces by repeated washing with water, and its antimicrobial activity could not be attributed to a slow release of the chemical, but rather to the surface-bonded chemical.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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