Strain-Specific Gifsy-1 Prophage Genes Are Determinants for Expression of the RNA Repair Operon during the SOS Response in Salmonella enterica Serovar Typhimurium-Reference-Cited by-同舟云学术

Strain-Specific Gifsy-1 Prophage Genes Are Determinants for Expression of the RNA Repair Operon during the SOS Response in Salmonella enterica Serovar Typhimurium

Published:2023-01-26 Issue:1 Volume:205 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Kurasz Jennifer E.¹,Crawford Madison C.¹,Porwollik Steffen²,Gregory Oliver¹,Tadlock Katerina R.¹,Balding Eve C.¹,Weinert Emily E.³^ORCID,McClelland Michael²,Karls Anna C.¹^ORCID

Affiliation:

1. Department of Microbiology, University of Georgia, Athens, Georgia, USA

2. Department of Microbiology and Molecular Genetics, University of California–Irvine School of Medicine, Irvine, California, USA

3. Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA

Abstract

The transcriptional activator RtcR and the RNA repair proteins whose expression it regulates, RtcA and RtcB, are widely conserved in Proteobacteria . In Salmonella Typhimurium 14028s, genotoxic stress activates RtcR to direct RpoN-dependent expression of the rsr-yrlBA-rtcBA operon.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of General Medical Sciences

U.S. Department of Agriculture

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00262-22

Reference50 articles.

1. The cyclic phosphodiesterase CNP and RNA cyclase RtcA fine-tune noncanonical XBP1 splicing during ER stress