Immune Responses and Viral Persistence in Simian/Human Immunodeficiency Virus SHIV.C.CH848-Infected Rhesus Macaques-Reference-Cited by-同舟云学术

Immune Responses and Viral Persistence in Simian/Human Immunodeficiency Virus SHIV.C.CH848-Infected Rhesus Macaques

Published:2021-04-12 Issue:9 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Ziani Widade¹,Bauer Anya²^ORCID,Lu Hong³,Wang Xiaolei¹,Wu Xueling³,Bar Katharine J.²,Li Hui²,Liu Dongfang⁴,Shaw George M.²,Veazey Ronald S.¹,Xu Huanbin¹^ORCID

Affiliation:

1. Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, USA

2. Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

3. Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA

4. Department of Pathology, Immunology and Laboratory Medicine, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA

Abstract

SHIVs have been extensively used in a nonhuman primate (NHP) model for HIV research. In this study, we investigated viral reservoirs in tissues and immune responses in an NHP model inoculated with newly generated transmitted/founder HIV-1 clade C-based SHIV.C.CH848.

Funder

HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development

HHS | NIH | National Center for Research Resources

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Dental and Craniofacial Research

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.02198-20

Reference103 articles.