One versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway-Reference-Cited by-同舟云学术

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One versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway

Published:2021-04-27 Issue:2 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Jean-Pierre Fabrice¹,Vyas Arsh²,Hampton Thomas H.¹,Henson Michael A.²³,O’Toole George A.¹^ORCID

Affiliation:

1. Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA

2. Department of Chemical Engineering, University of Massachusetts, Amherst, Massachusetts, USA

3. Institute for Applied Life Sciences, University of Massachusetts, Amherst, Massachusetts, USA

Abstract

Culture-independent studies have revealed that chronic lung infections in persons with cystic fibrosis (pwCF) are rarely limited to one microbial species. Interactions among bacterial members of these polymicrobial communities in the airways of pwCF have been reported to modulate clinically relevant phenotypes.

Funder

HHS | National Institutes of Health

DOD | United States Army | RDECOM | Army Research Office

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00006-21

Reference44 articles.

1. New concepts of the pathogenesis of cystic fibrosis lung disease

2. The Cystic Fibrosis Lung Microbiome

3. Interplay between host-microbe and microbe-microbe interactions in cystic fibrosis

4. Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms

5. The social life of microbes in chronic infection

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