Antifungal Liposomes Directed by Dectin-2 Offer a Promising Therapeutic Option for Pulmonary Aspergillosis

Author:

Ambati Suresh1,Ellis Emma C.1,Pham Tuyetnhu2,Lewis Zachary A.2ORCID,Lin Xiaorong2ORCID,Meagher Richard B.1

Affiliation:

1. Department of Genetics, University of Georgia, Athens, Georgia, USA

2. Department of Microbiology, University of Georgia, Athens, Georgia, USA

Abstract

Invasive aspergillosis (IA) generally results from a pulmonary infection of immunocompromised patients by the common soil organism and opportunistic pathogen Aspergillus fumigatus . The susceptible population has expanded rapidly due to the increased number of cancer patients with immunocompromising chemotherapy and transplant patients taking immunosuppressants.

Funder

University of Georgia

UGA | University of Georgia Research Foundation

HHS | NIH | NIAID | Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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