Effective Generation of Glucosylpiericidins with Selective Cytotoxicities and Insights into Their Biosynthesis-Reference-Cited by-同舟云学术

Effective Generation of Glucosylpiericidins with Selective Cytotoxicities and Insights into Their Biosynthesis

Published:2021-06-11 Issue:13 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Liu Zengzhi¹,Xiao Fei¹,Cai Siqi¹,Liu Chunni¹,Li Huayue¹²,Wu Ting¹,Jiang Yuechen¹,Wang Xin¹²,Che Qian¹²,Zhu Tianjiao¹²,Li Dehai¹²,Li Wenli¹²^ORCID

Affiliation:

1. Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China

2. Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China

Abstract

Numerous bioactive natural products are appended with sugar moieties and are often critical for their bioactivities. Glycosyltransferases (GTs) are powerful tools for the glycodiversification of natural products.

Funder

the National Key R & D Program of China

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00294-21

Reference35 articles.

1. Glycosyltransferases: Structures, Functions, and Mechanisms

2. Glycosyltransferases, Important Tools for Drug Design

3. Biosynthese von Naturstoffzuckern und enzymatische Glycodiversifizierung

4. Natural Product Glycosyltransferases: Properties and Applications

5. Exploiting the Reversibility of Natural Product Glycosyltransferase-Catalyzed Reactions

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