Biofilm Formation and Virulence of Shigella flexneri Are Modulated by pH of Gastrointestinal Tract-Reference-Cited by-同舟云学术

Biofilm Formation and Virulence of Shigella flexneri Are Modulated by pH of Gastrointestinal Tract

Published:2021-10-15 Issue:11 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Chiang I-Ling¹,Wang Yi¹,Fujii Satoru²,Muegge Brian D.³⁴,Lu Qiuhe²,Tarr Phillip I.⁵⁶,Stappenbeck Thaddeus S.²^ORCID

Affiliation:

1. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA

2. Department of Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA

3. Division of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA

4. St. Louis VA Medical Center, St. Louis, Missouri, USA

5. Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA

6. Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA

Abstract

Shigella infection remains a public health problem in much of the world. Classic models of Shigella pathogenesis suggest that microfold epithelial cells in the small intestine are the preferred initial site of invasion.

Funder

Crohn's and Colitis Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00387-21

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