A Novel Pneumococcal Surface Protein K of Nonencapsulated <i>Streptococcus pneumoniae</i> Promotes Transmission among Littermates in an Infant Mouse Model with Influenza A Virus Coinfection-Reference-Cited by-同舟云学术

A Novel Pneumococcal Surface Protein K of Nonencapsulated Streptococcus pneumoniae Promotes Transmission among Littermates in an Infant Mouse Model with Influenza A Virus Coinfection

Published:2022-02-17 Issue:2 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Sakatani Hideki¹,Kono Masamitsu¹,Nanushaj Denisa¹,Murakami Daichi¹,Takeda Saori¹,Kaneko Fumie¹,Nahm Moon H.²,Hotomi Muneki¹^ORCID

Affiliation:

1. Department of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan

2. Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA

Abstract

We established an infant mouse model for colonization and transmission by nonencapsulated Streptococcus pneumoniae (NESp) strains to gain important information about its virulence among children. Invasive pneumococcal diseases have decreased dramatically since the worldwide introduction of pneumococcal capsular polysaccharide vaccines. Increasing prevalence of nonvaccine serotypes, including NESp, has been highlighted as a challenge in treatment strategy, but the virulence of NESp is not well understood.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00622-21

Reference44 articles.

1. Novel Strategy to Prevent Otitis Media Caused by Colonizing Streptococcus pneumoniae

2. Infections Caused by Streptococcus pneumoniae: Clinical Spectrum, Pathogenesis, Immunity, and Treatment

3. Recommendations for Pneumococcal Immunization Outside Routine Childhood Immunization Programs in Western Europe

4. Decline in Invasive Pneumococcal Disease after the Introduction of Protein–Polysaccharide Conjugate Vaccine

5. Effect of Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization among Immunized and Unimmunized Children in a Community‐Randomized Trial

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