Affiliation:
1. Department of Molecular Biology and Biotechnology, University of Sheffield, United Kingdom.
Abstract
The gene encoding the major autolysin of Staphylococcus aureus 8325/4 has been cloned, sequenced, and insertionally inactivated. The three-domain, 137,384-Da protein has a C-terminal glucosaminidase active site and is involved in cell separation, generalized cell lysis, and release of wall material at the cell surface. Expression occurs throughout growth and is stimulated by low temperatures and in the presence of 1 M NaCl.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
129 articles.
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