Porins and Lipopolysaccharide Induce Apoptosis in Human Spermatozoa

Author:

Gorga Fernanda1,Galdiero Marilena1,Buommino Elisabetta1,Galdiero Emilia2

Affiliation:

1. Istituto di Microbiologia, Facoltà di Medicina e Chirurgia, Seconda Università degli Studi di Napoli,1 and

2. Dipartimento Fisiologia Generale ed Ambientale, Sezione Igiene e Microbiologia, Università degli Studi di Napoli Federico II,2 80138 Napoli, Italy

Abstract

ABSTRACT Treatment of human spermatozoa with porins or lipopolysaccharide (LPS) increases spontaneous apoptosis in these cells. Porins and LPS were extracted from Salmonella enterica serovar Typhimurium and Pasteurella multocida and were mixed with human spermatozoa for detection of levels of apoptosis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Reference23 articles.

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2. Apoptosis in human ejaculated sperm cells (notulae seminologicae).;Bacetti B.;J. Submicrosc. Cytol. Pathol.,1996

3. Apoptosis in testis germ cells: developmental changes in gonadotropin dependence and localization to selective tubule stages.;Billig H.;Endocrinology,1995

4. Interferon-gamma induction by lipopolysaccharide: dependence on interleukin-2 and macrophages.;Blanchard D. K.;J. Immunol.,1986

5. The cell envelop of gram-negative bacteria: new aspects of its function in transport and chemotaxis.;Brass J. M.;Curr. Top. Microbiol. Immunol.,1986

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