Postinfection Metabolic Reprogramming of the Murine Trigeminal Ganglion Limits Herpes Simplex Virus-1 Replication-Reference-Cited by-同舟云学术

Postinfection Metabolic Reprogramming of the Murine Trigeminal Ganglion Limits Herpes Simplex Virus-1 Replication

Published:2022-10-26 Issue:5 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Patil Chandrashekhar D.¹^ORCID,Suryawanshi Rahul K.¹,Kapoor Divya¹²,Shukla Deepak¹²^ORCID

Affiliation:

1. Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA

2. Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois, USA

Abstract

The more severe ocular pathologies associated with HSV-1 infection are significant vision loss, ocular morbidity, and herpetic keratitis. The current clinical landscape lacks curative drugs and vaccines against HSV-1, a heavy burden associated with this neurotropic, ubiquitous pathogen.

Funder

HHS | NIH | National Eye Institute

HHS | NIH | National Institute of Allergy and Infectious Diseases

Illinois Society for the Prevention of Blindness

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02194-22

Reference32 articles.

1. Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry