Identification of Antifungal Compounds against Multidrug-Resistant Candida auris Utilizing a High-Throughput Drug-Repurposing Screen-Reference-Cited by-同舟云学术

Identification of Antifungal Compounds against Multidrug-Resistant Candida auris Utilizing a High-Throughput Drug-Repurposing Screen

Published:2021-03-18 Issue:4 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Cheng Yu-Shan¹,Roma Jose Santinni²,Shen Min¹,Mota Fernandes Caroline³,Tsang Patricia S.²,Forbes He Eun²,Boshoff Helena²,Lazzarini Cristina³,Del Poeta Maurizio³⁴⁵^ORCID,Zheng Wei¹^ORCID,Williamson Peter R.²

Affiliation:

1. National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, USA

2. Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

3. Department of Microbiology and Immunology, Stony Brook University, Stony Brook, New York, USA

4. Division of Infectious Diseases, Stony Brook University, Stony Brook, New York, USA

5. Veterans Affairs Medical Center, Northport, New York, USA

Abstract

Candida auris is an emerging fatal fungal infection that has resulted in several outbreaks in hospitals and care facilities. Current treatment options are limited by the development of drug resistance.

Funder

Veterans Affairs Program Merit Review Grant

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

HHS | NIH | National Center for Advancing Translational Sciences

HHS | NIH | OSC | Common Fund

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01305-20

Reference51 articles.