PheP, a Putative Amino Acid Permease of Staphylococcus aureus , Contributes to Survival In Vivo and during Starvation-Reference-Cited by-同舟云学术

PheP, a Putative Amino Acid Permease of Staphylococcus aureus , Contributes to Survival In Vivo and during Starvation

Published:2004-05 Issue:5 Volume:72 Page:3073-3076
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Horsburgh Malcolm J.¹,Wiltshire Michael D.¹,Crossley Howard¹,Ingham Eileen²,Foster Simon J.¹

Affiliation:

1. Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, S10 2TN

2. Division of Microbiology, University of Leeds, Leeds, LS2 9JT, United Kingdom

Abstract

ABSTRACT PheP, a putative amino acid permease in Staphylococcus aureus , contributes to starvation survival under glucose-limiting conditions and virulence. A pheP mutation led to poor growth after microaerobic or anaerobic incubation on pig serum agar, which was recovered by phenylalanine addition. Genetic complementation of pheP restored growth and starvation survival.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.72.5.3073-3076.2004

Reference24 articles.

1. Impact of the High-Affinity Proline Permease Gene ( putP ) on the Virulence of Staphylococcus aureus in Experimental Endocarditis

2. Brook, I., and E. H. Frazier. 1990. Aerobic and anaerobic bacteriology of wounds and cutaneous abscesses. Arch. Surg.125:1445-1451.

3. Role of SarA in Virulence Determinant Production and Environmental Signal Transduction in Staphylococcus aureus

4. Coulter, S. N., W. R. Schwan, E. Y. Ng, M. H. Langhorne, H. D. Ritchie, S. Westbrock-Wadman, W. O. Hufnagle, K. R. Folger, A. S. Bayer, and C. K. Stover. 1998. Staphylococcus aureus genetic loci impacting growth and survival in multiple infection environments. Mol. Microbiol.30:393-404.

5. Guerot-Fleury, A.-M., N. Shazand, N. Frandsen, and P. Stragier. 1995. Antibiotic resistance cassettes for Bacillus subtilis. Gene167:335-336.

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Transcriptomic responses and survival mechanisms of staphylococci to the antimicrobial skin lipid sphingosine;Antimicrobial Agents and Chemotherapy;2021-12-13

2. Exploring amino acid and peptide transporters as therapeutic targets to attenuate virulence and antibiotic resistance in Staphylococcus aureus;PLOS Pathogens;2021-01-14

3. Transcriptomic responses and survival mechanisms of staphylococci to the antimicrobial skin lipid sphingosine;2020-09-15

4. Human skin commensals augment Staphylococcus aureus pathogenesis;Nature Microbiology;2018-07-16

5. Comparative Transcriptomics Reveals Discrete Survival Responses of S. aureus and S. epidermidis to Sapienic Acid;Frontiers in Microbiology;2017-01-25