Generation of leukotrienes from human granulocytes by alveolysin from Bacillus alvei-Reference-Cited by-同舟云学术

Generation of leukotrienes from human granulocytes by alveolysin from Bacillus alvei

Published:1984-04 Issue:1 Volume:44 Page:188-193
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Bremm K D,Brom H J,Alouf J E,König W,Spur B,Crea A,Peters W

Abstract

We investigated the effect of alveolysin on human granulocytes. Alveolysin is an exoprotein produced by Bacillus alvei and belongs to the group of sulfhydryl-activated cytolysins. Other members of this group are streptolysin O and theta-toxin from Clostridium perfringens. It is demonstrated that alveolysin leads to leukotriene generation from human granulocytes, which exert chemotactic (leukotriene B4) and slow-reacting substance (leukotriene C4, D4, and E4) activity under sublytic concentrations.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.44.1.188-193.1984

Reference34 articles.

1. Bacterial toxins: an outlook;Alouf J. E.;Toxicon,1982

2. Lipoxygenase-derived products of arachidonic acid mediate stimulation of hexose uptake in human polymorphonuclear leukocytes;Bass D. A.;Biochem. Biophys. Res. Commun.,1981

3. Interaction between membranes and cytolytic bacterial toxins;Bernheimer A. W.;Biochim. Biophys. Acta,1974

4. Staphylococcal alpha-toxin: olgiomerisation of hydrophilic monomers to form amphiphilic hexamers induced through contact with deoxycholat detergent miscelles;Bhakdi S.;Proc. Natl. Acad. Sci. U.S.A.,1981

5. Leukotriene B4: a mediator of vascular permeability;Bray M. A.;Br. J. Pharmacol.,1981

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