FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease-Reference-Cited by-同舟云学术

FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease

Published:2022-10-20 Issue:10 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Camire Andrew C.¹,O’Bier Nathaniel S.¹,Patel Dhara T.¹,Cramer Nicholas A.¹,Straubinger Reinhard K.²,Breitschwerdt Edward B.³,Funk Rebecca A.⁴,Marconi Richard T.¹⁵^ORCID

Affiliation:

1. Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA

2. Institute of Infectious Diseases and Zoonoses, Department of Veterinary Sciences, Faculty of Veterinary Medicine, Ludwig-Maximilians-University, Munich, Germany

3. Department of Clinical Sciences, The Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA

4. Department of Large Animal Clinical Sciences, VA-MD College of Veterinary Medicine, Blacksburg, Virginia, USA

5. Department of Oral and Craniofacial Molecular Biology, Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, Virginia, USA

Abstract

Lyme disease (LD) is a tick-transmitted bacterial infection caused by Borreliella burgdorferi and other closely related species collectively referred to as the LD spirochetes. The LD spirochetes encode an uncharacterized family of proteins originally designated p rotein f amily t welve (PF12).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00364-22

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