Comparative Study of Seven Picornaviruses of Man

Author:

Jamison Richard M.1,Mayor Heather D.1

Affiliation:

1. World Health Organization, International Centre for Enteroviruses, Department of Virology and Epidemiology, Baylor University College of Medicine, Houston, Texas

Abstract

Jamison, Richard M. (Baylor University College of Medicine, Houston, Tex.), and Heather D. Mayor . Comparative study of seven picornaviruses of man. J. Bacteriol. 91: 1971–1976. 1966.—The buoyant densities in CsCl and potassium tartrate of seven acid-resistant picornaviruses of man were determined. The viruses studied were found to be a relatively homogeneous group. Buoyant densities ranged from 1.32 to 1.35 g/cc in CsCl and 1.21 to 1.23 g/cc in potassium tartrate. The buoyant density of each virus did not vary by more than 0.01 g/cc. The host cell of origin and passage level did not influence the buoyant density of the virions. However, measurements of the diameters of purified virions by a standard method have shown that there are considerable size variations among these picornaviruses. The diameters ranged from 18 to 25 mμ. Echovirus 19 and poliovirus 1 were significantly larger (mean diameter, 23.5 mμ) than echoviruses 4, 6, 16, and 23, and coxsackievirus B2 (mean diameter, 21.0 mμ).

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference19 articles.

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