The Vibrio harveyi GTPase CgtA V Is Essential and Is Associated with the 50S Ribosomal Subunit-Reference-Cited by-同舟云学术

The Vibrio harveyi GTPase CgtA V Is Essential and Is Associated with the 50S Ribosomal Subunit

Published:2006-02 Issue:3 Volume:188 Page:1205-1210
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Sikora A. E.¹²,Zielke R.¹²,Datta K.¹,Maddock J. R.¹

Affiliation:

1. Department of Molecular, Cellular and Developmental Biology, University of Michigan, 830 North University, Ann Arbor, Michigan 48109

2. Department of Molecular Biology, University of Gdansk, Kładki 24, 80-822 Gdansk, Poland

Abstract

ABSTRACT It was previously reported that unlike the other obg/cgtA GTPases, the Vibrio harveyi cgtA V is not essential. Here we show that cgtA V was not disrupted in these studies and is, in fact, essential for viability. Depletion of CgtA V did not result in cell elongation. CgtA V is associated with the large ribosomal particle. In light of our results, we predict that the V. harveyi CgtA V protein plays a similar essential role to that seen for Obg/CgtA proteins in other bacteria.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.188.3.1205-1210.2006

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