Genomic Diversity of Azole-Resistant Aspergillus fumigatus in the United States-Reference-Cited by-同舟云学术

Genomic Diversity of Azole-Resistant Aspergillus fumigatus in the United States

Published:2021-08-31 Issue:4 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Etienne Kizee A.¹²,Berkow Elizabeth L.¹,Gade Lalitha¹,Nunnally Natalie¹^ORCID,Lockhart Shawn R.¹,Beer Karlyn¹,Jordan I. King²,Rishishwar Lavanya²,Litvintseva Anastasia P.¹

Affiliation:

1. Mycotic Diseases Branch, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA

2. School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA

Abstract

Aspergillus fumigatus is one of the most common causes of invasive mold infections in patients with immune deficiencies and has also been reported in patients with severe influenza and severe acute respiratory syndrome coronavirus 2 (SARs-CoV-2). Triazole drugs are the first line of therapy for this infection; however, their efficacy has been compromised by the emergence of azole resistance in A. fumigatus , which was proposed to be selected for by exposure to azole fungicides in the environment [P.

Funder

IHRC-Georgia Tech Applied Biotechnology Laboratory

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.01803-21

Reference54 articles.

1. Clinical implications of globally emerging azole resistance in Aspergillus fumigatus

2. Invasive Aspergillosis Associated With Severe Influenza Infection

3. Invasive Aspergillosis in Critically Ill Patients without Malignancy