Role of Dectin-2 in the Phagocytosis of Cryptococcus neoformans by Dendritic Cells-Reference-Cited by-同舟云学术

Role of Dectin-2 in the Phagocytosis of Cryptococcus neoformans by Dendritic Cells

Published:2021-09-16 Issue:10 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Kitai Yuki¹,Sato Ko²^ORCID,Tanno Daiki¹,Yuan Xiaoliang¹,Umeki Aya¹,Kasamatsu Jun²,Kanno Emi³,Tanno Hiromasa³,Hara Hiromitsu⁴,Yamasaki Sho⁵⁶⁷⁸,Saijo Shinobu⁸,Iwakura Yoichiro⁹,Ishii Keiko¹,Kawakami Kazuyoshi¹²

Affiliation:

1. Department of Medical Microbiology, Mycology, and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

2. Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

3. Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

4. Department of Immunology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan

5. Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan

6. Laboratory of Molecular Immunology, Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan

7. Division of Molecular Design, Research Center for Systems Immunology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

8. Division of Molecular Immunology, Medical Mycology Research Center, Chiba University, Chiba, Japan

9. Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba, Japan

Abstract

The cell walls and capsules of Cryptococcus neoformans , a yeast-type fungal pathogen, are rich in polysaccharides. Dectin-2 is a C-type lectin receptor (CLR) that recognizes high-mannose polysaccharides.

Funder

MEXT | JST | Strategic International Collaborative Research Program

MSD Life Science Foundation, Public Interest Incorporated Foundation

Ministry of Education, Culture, Sports, Science and Technology

Chiba University

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00330-21