Impact of Hepatitis C Virus (HCV) Genotypes on Quantification of HCV RNA in Serum by COBAS AmpliPrep/COBAS TaqMan HCV Test, Abbott Antiretroviral Therapy HCV RealTime Assay, and VERSANT HCV RNA Assay-Reference-Cited by-同舟云学术

Impact of Hepatitis C Virus (HCV) Genotypes on Quantification of HCV RNA in Serum by COBAS AmpliPrep/COBAS TaqMan HCV Test, Abbott Antiretroviral Therapy HCV RealTime Assay, and VERSANT HCV RNA Assay

Published:2007-09 Issue:9 Volume:45 Page:3077-3081
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Tuaillon Edouard¹,Mondain Anne-Marie¹,Ottomani Laure¹,Roudière Laurent¹,Perney Pascal²,Picot Marie-Christine³,Séguret Fabienne³,Blanc François²,Larrey Dominique⁴,Van de Perre Philippe¹,Ducos Jacques¹

Affiliation:

1. Unité Hépatites Virales, Laboratoire de Virologie, Hôpital Lapeyronie

2. Service de Médecine Interne E

3. Département de l'Informatique Médicale Hôpital Arnaud de Villeneuve, CHU de Montpellier, France

4. Institut des Maladies de l'Appareil Digestif, Hôpital Saint-Eloi

Abstract

ABSTRACT The VERSANT HCV RNA 3.0 (bDNA), COBAS AmpliPrep/COBAS TaqMan HCV, and Abbott ART HCV RealTime assays were compared for hepatitis C virus RNA quantification in 158 clinical specimens (genotypes 1 to 5). RNA values differed significantly between methods ( P < 0.0001), and mean titer differences ranged from 0.01 to 0.50 log 10 IU/ml depending on the genotypes.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00111-07

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