Metabolism of Linoleic Acid by Human Gut Bacteria: Different Routes for Biosynthesis of Conjugated Linoleic Acid

Author:

Devillard Estelle1,McIntosh Freda M.1,Duncan Sylvia H.1,Wallace R. John1

Affiliation:

1. Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, AB21 9SB, United Kingdom

Abstract

ABSTRACT A survey of 30 representative strains of human gram-positive intestinal bacteria indicated that Roseburia species were among the most active in metabolizing linoleic acid ( cis -9, cis- 12-18:2). Different Roseburia spp. formed either vaccenic acid ( trans- 11-18:1) or a 10-hydroxy-18:1; these compounds are precursors of the health-promoting conjugated linoleic acid cis- 9, trans- 11-18:2 in human tissues and the intestine, respectively.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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