Differential Antibiotic Susceptibilities of Starved Mycobacterium tuberculosis Isolates-Reference-Cited by-同舟云学术

Differential Antibiotic Susceptibilities of Starved Mycobacterium tuberculosis Isolates

Published:2005-11 Issue:11 Volume:49 Page:4778-4780
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Xie Zhifang¹,Siddiqi Noman¹,Rubin Eric J.¹

Affiliation:

1. Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts

Abstract

ABSTRACT We compared the efficacies of 17 agents against rapidly growing and starved Mycobacterium tuberculosis H37Rv. Few compounds have significant activity at attainable concentrations. However, two phenothiazine compounds at similar concentrations were bactericidal for starved and growing cells. These drugs appear to target a process important in both replicating and nonreplicating bacteria.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.11.4778-4780.2005

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