Increased Mutation Frequencies in Escherichia coli Isolates Harboring Extended-Spectrum β-Lactamases-Reference-Cited by-同舟云学术

Increased Mutation Frequencies in Escherichia coli Isolates Harboring Extended-Spectrum β-Lactamases

Published:2005-11 Issue:11 Volume:49 Page:4754-4756
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Baquero María-Rosario¹,Galán Juan Carlos¹,del Carmen Turrientes María¹,Cantón Rafael¹,Coque Teresa M.¹,Martínez José Luis¹,Baquero Fernando¹

Affiliation:

1. Department of Microbiology, Ramón y Cajal University Hospital, and Centro Nacional de Biotecnología (CSIC-RYC Associated Unit on Antibiotic Resistance and Bacterial Virulence), 28034 Madrid, Spain

Abstract

ABSTRACT Hypermutable (mutation frequency [ f ], ≥4 × 10 −8 ) Escherichia coli strains were more frequently found (43%) in a collection of 89 extended-spectrum β-lactamase (ESBL)-producing isolates from different patients (77 pulsed-field gel electrophoresis clones, 12 ESBL types) than in non-ESBL E. coli (26%) strains ( P = 0.03). Among urinary tract isolates, the frequency of hypermutation was 40% in ESBL versus 26% in non-ESBL isolates ( P = 0.03).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.11.4754-4756.2005

Reference26 articles.

1. Microcin plasmids: a group of extrachromosomal elements coding for low-molecular-weight antibiotics in Escherichia coli

2. Polymorphic Mutation Frequencies in Escherichia coli : Emergence of Weak Mutators in Clinical Isolates

3. Bastarrachea, F. 1998. On the origin of plasmid-borne, extended-spectrum, antibiotic resistance mutations in bacteria. J. Theor. Biol.190:379-387.

4. Blázquez, J. 2003. Hypermutation as a factor contributing to the acquisition of antimicrobial resistance. Clin. Infect. Dis.37:1201-1209.

5. Growing Group of Extended-Spectrum β-Lactamases: the CTX-M Enzymes

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