Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein-Reference-Cited by-同舟云学术

Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein

Published:1990-03 Issue:3 Volume:64 Page:1353-1356
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Dyson N¹,Bernards R¹,Friend S H¹,Gooding L R¹,Hassell J A¹,Major E O¹,Pipas J M¹,Vandyke T¹,Harlow E¹

Affiliation:

1. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724.

Abstract

Stable protein complexes between the large T antigens of mouse, monkey, baboon, or human polyomaviruses and the retinoblastoma protein were detected by an in vitro coimmunoprecipitation assay. All of the large T antigens tested were able to bind to both human and mouse retinoblastoma polypeptides, showing that these interactions have been conserved during evolution.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.64.3.1353-1356.1990

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