Drown them in their own garbage: a new strategy to reverse polymyxin resistance?-Reference-Cited by-同舟云学术

Drown them in their own garbage: a new strategy to reverse polymyxin resistance?

Published:2021-11-29 Issue: Volume: Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

May Kerrie L.¹²³

Affiliation:

1. Emory Antibiotic Resistance Center, Emory University School of Medicine, Atlanta, GA 30322

2. Department of Microbiology & Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.

3. Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

Abstract

Purcell and colleagues offer new insights into a major mechanism of polymyxin resistance in Gram-negative bacteria. Inactivating a single lipid recycling enzyme causes accumulation of waste lipid by-products that inhibit a key factor responsible for polymyxin resistance.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00574-21

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