Efficacy of Different β-Lactams against an Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Strain in the Rat Intra-Abdominal Abscess Model-Reference-Cited by-同舟云学术

Efficacy of Different β-Lactams against an Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Strain in the Rat Intra-Abdominal Abscess Model

Published:1991-06 Issue:6 Volume:35 Page:1243-1244
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Rice Louis B.¹²,Yao Joseph D. C.¹²,Klimm Karin¹,Eliopoulos George M.¹²,Moellering Robert C.¹²

Affiliation:

1. Infectious Disease Section and Department of Medicine, New England Deaconess Hospital, Boston, Massachusetts 02215

2. Harvard Medical School, Boston, Massachusetts 02215

Abstract

Although standard-inoculum MICs were within the susceptible range for all compounds, cefoperazone, cefotaxime, and cefpirome were significantly less effective than imipenem or the combination of cefoperazone and sulbactam in the treatment of rat intra-abdominal abscesses due to an extended-spectrum β-lactamase-producing strain of Klebsiella pneumoniae .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.35.6.1243

Reference8 articles.

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2. Activity of sulbactam in combination with ceftriaxone in vitro and in experimental endocarditis caused by Escherichia coli producing SHV-like P-lactamase;Fantin B.;Antimicrob. Agents Chemother.,1990

3. Comparing means of several groups;Godfrey K.;N. Engl. J. Med.,1985

4. Jones R. N. A. L. Barry T. L. Gavan and J. A. Washington II. 1985. Susceptibility tests: microdilution and macrodilution broth procedures p. 972-977. In E. H. Lennette A. Balows W. J. Hausler Jr. and H. J. Shadomy (ed.) Manual of clinical microbiology 4th ed. American Society for Microbiology Washington D.C.

5. Outbreak of ceftazidime resistance caused by extended-spectrum P-lactamases at a Massachusetts chronic care facility;Rice L. B.;Antimicrob. Agents Chemother.,1990

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