A Temperature-Sensitive Recombinant of Avian Coronavirus Infectious Bronchitis Virus Provides Complete Protection against Homologous Challenge-Reference-Cited by-同舟云学术

A Temperature-Sensitive Recombinant of Avian Coronavirus Infectious Bronchitis Virus Provides Complete Protection against Homologous Challenge

Published:2022-09-14 Issue:17 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Keep Sarah¹^ORCID,Stevenson-Leggett Phoebe¹,Dowgier Giulia¹,Foldes Katalin¹,Webb Isobel¹,Fones Albert¹,Littolff Kieran¹,Everest Holly¹,Britton Paul¹,Bickerton Erica¹^ORCID

Affiliation:

1. The Pirbright Institute, Surrey, United Kingdom

Abstract

Infectious bronchitis virus is a pathogen of economic and welfare concern for the global poultry industry. Live-attenuated vaccines against are generated by serial passage of a virulent isolate in embryonated eggs until attenuation is achieved.

Funder

UKRI | Biotechnology and Biological Sciences Research Council

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01100-22

Reference79 articles.

1. The long view: 40 years of infectious bronchitis research

2. Infectious bronchitis virus: Immunopathogenesis of infection in the chicken

3. Ability of Massachusetts-type infectious bronchitis virus to increase colibacillosis susceptibility incommercial broilers: A comparison between vaccine and virulent field virus