Multidrug-Resistant Strains of Neisseria gonorrhoeae in Greece

Author:

Mavroidi Angeliki1,Tzouvelekis Leonidas S.2,Kyriakis Kyriakos P.1,Avgerinou Helen3,Daniilidou Maria4,Tzelepi Eva1

Affiliation:

1. National Reference Center for Neisseria gonorrhoeae, Department of Bacteriology, Hellenic Pasteur Institute,1

2. Laboratory of Antimicrobial Agents, Department of Microbiology, Athens University Medical School,2 and

3. Microbiology Laboratory, “Andreas Sygros” Hospital for Skin and Venereal Diseases,3 Athens, and

4. Microbiology Laboratory, Venereal Hospital of Thessaloniki, Thessaloniki,4 Greece

Abstract

ABSTRACT Eighty-seven out of 575 gonococci isolated in Greece from 1991 to 1998 belonged to serovar Bropyst and exhibited resistance to penicillin, tetracycline, erythromycin, and chloramphenicol. Conventional and molecular typing showed three clusters, A, B, and C, that were associated with networks of high- frequency transmitters (cluster A with homosexuals and clusters B and C with refugees from Eastern Europe). Study of one isolate revealed mutations in the penA, mtrR , and porB genes that may explain the multidrug-resistant phenotype.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference19 articles.

1. Insertion of an extra amino acid is the main cause of the low affinity of penicillin-binding protein 2 in penicillin-resistant strains of Neisseria gonorrhoeae.;Brannigan J. A.;Mol. Microbiol.,1990

2. Gonorrhea among men who have sex with men—selected sexually transmitted diseases clinics, 1993–1996.;Centers for Disease Control and Prevention;Morb. Mortal. Wkly. Rep.,1997

3. Penicillin-binding protein 2 genes of non-β-lactamase-producing, penicillin-resistant strains of Neisseria gonorrhoeae.;Dowson C. G.;Mol. Microbiol.,1989

4. The changing pattern of antibiotic resistance of Neisseria gonorrhoeae.;Easmon C. S. F.;Genitourin. Med.,1990

5. Gonococcal Resistance to β-Lactams and Tetracycline Involves Mutation in Loop 3 of the Porin Encoded at the penB Locus

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3