SARS-CoV-2 Exposure in Norway Rats (Rattus norvegicus) from New York City

Author:

Wang Yang123,Lenoch Julianna4,Kohler Dennis4,DeLiberto Thomas J.5,Tang Cynthia Y.123ORCID,Li Tao6,Tao Yizhi Jane7ORCID,Guan Minhui123ORCID,Compton Susan8,Zeiss Caroline8,Hang Jun6ORCID,Wan Xiu-Feng1239ORCID

Affiliation:

1. Center for Influenza and Emerging Infectious Diseases, University of Missouri, Columbia, Missouri, USA

2. Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, Missouri, USA

3. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, USA

4. USDA APHIS Wildlife Services National Wildlife Disease Program, Fort Collins, Colorado, USA

5. USDA APHIS Wildlife Services, Fort Collins, Colorado, USA

6. Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA

7. Department of BioSciences, Rice University, Houston, Texas, USA

8. School of Medicine, Yale University, New Haven, Connecticut, USA

9. Department of Electrical Engineering & Computer Science, College of Engineering, University of Missouri, Columbia, Missouri, USA

Abstract

The host tropism expansion of SARS-CoV-2 raises concern for the potential risk of reverse-zoonotic transmission of emerging variants into rodent species, including wild rat species. In this study, we present both genetic and serological evidence for SARS-CoV-2 exposure to the New York City wild rat population, and these viruses may be linked to the viruses that were circulating during the early stages of the pandemic.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

U.S. Department of Agriculture

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Reference31 articles.

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