Deletion of African Swine Fever Virus (ASFV) H240R Gene Attenuates the Virulence of ASFV by Enhancing NLRP3-Mediated Inflammatory Responses-Reference-Cited by-同舟云学术

Deletion of African Swine Fever Virus (ASFV) H240R Gene Attenuates the Virulence of ASFV by Enhancing NLRP3-Mediated Inflammatory Responses

Published:2023-02-28 Issue:2 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Huang Li¹²,Liu Hongyang¹,Ye Guangqiang¹,Liu Xiaohong¹,Chen Weiye¹,Wang Zilong¹,Zhao Dongming¹,Zhang Zhaoxia¹²,Feng Chunying¹,Hu Liang¹,Yu Huibin³,Zhou Shijun¹,Zhang Xianfeng¹,He Xijun¹,Zheng Jun¹²,Bu Zhigao¹^ORCID,Li Jiangnan¹²,Weng Changjiang¹²

Affiliation:

1. Division of Fundamental Immunology, National African Swine Fever Para-reference Laboratory, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

2. Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin, China

3. Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA

Abstract

African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and acute hemorrhagic viral disease of domestic pigs, with a high mortality approaching 100%. ASFV has spread rapidly worldwide and caused huge economic losses and ecological consequences.

Funder

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01227-22

Reference38 articles.

1. An Update on African Swine Fever Virology

2. African swine fever: how can global spread be prevented?