Alteration of rabbit alveolar and peritoneal macrophage function by herpes simplex virus

Author:

Plaeger-Marshall S,Wilson L A,Smith J W

Abstract

Exposure of rabbit alveolar and peritoneal macrophages to infectious herpes simplex virus resulted in inhibition of antibody-dependent cellular cytotoxicity and either enhancement or inhibition of phagocytosis. At all times after exposure, virus was inhibitory to peritoneal macrophage phagocytosis. Alveolar macrophages showed enhanced phagocytic activity in the early stages of virus exposure and inhibition at later time points.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference33 articles.

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2. Cheng Y. C. and D. Falke. 1981. Enzymology and physiology of herpesvirus infected cells p. 580-582. In A. J. Nahmias W. R. Dowdle and R. F. Schinazi (ed.) The human Herpesviruses: an interdisciplinary perspective. Elsevier/North-Holland Publishing Co. New York.

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