Molecular characterization of the genes encoding pyruvate formate-lyase and its activating enzyme of Clostridium pasteurianum

Author:

Weidner G1,Sawers G1

Affiliation:

1. Department of Microbiology and Genetics, University of Munich, Germany.

Abstract

Formate is the major source of C1 units in many species of the genus Clostridium. In this study we have cloned and characterized the genes encoding pyruvate formate-lyase and its activating enzyme of Clostridium pasteurianum. The genetic and transcriptional organizations of the genes and the high level of homology exhibited by the respective gene products to their Escherichia coli counterparts indicate strong evolutionary conservation of these enzymes.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference37 articles.

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