Tet determinants provide poor protection against some tetracyclines: further evidence for division of tetracyclines into two classes-Reference-Cited by-同舟云学术

Tet determinants provide poor protection against some tetracyclines: further evidence for division of tetracyclines into two classes

Published:1992-04 Issue:4 Volume:36 Page:876-878
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Oliva B¹,Chopra I¹

Affiliation:

1. Department of Microbial Biochemistry and Genetics, American Cyanamid, Lederle Laboratories, Pearl River, New York 10965.

Abstract

Atypical tetracyclines were active against Escherichia coli and Staphylococcus aureus strains containing determinants that mediate resistance to typical tetracyclines by efflux (Tet B and Tet K) or ribosomal protection (Tet M) mechanisms. The results support recently published data that tetracyclines are divisible into at least two classes on the basis of their modes of action.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.36.4.876

Reference16 articles.

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5. Effects of tetracyclines on the production of extracellular proteins by members of the propionibacteriaceae;Chopra I.;FEMS Microbiol. Lett.,1989

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