In Vitro MIC Values of Rifampin and Ethambutol and Treatment Outcome in Mycobacterium avium Complex Lung Disease

Author:

Kwon Byoung Soo1,Kim Mi-Na2ORCID,Sung Heungsup2,Koh Younsuck1,Kim Woo-Sung1,Song Jin-Woo1,Oh Yeon-Mok1,Lee Sang-Do1,Lee Sei Won1,Lee Jae-Seung1,Lim Chae-Man1,Choi Chang-Min1,Huh Jin-Won1,Hong Sang-Bum1,Park Sojung3,Shim Tae Sun1,Chong Yong Pil4,Jo Kyung-Wook1

Affiliation:

1. Division of Pulmonology and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

2. Department of Laboratory Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

3. Department of Pulmonary, Allergy, and Critical Care Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong-si, South Korea

4. Department of Infectious Diseases, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

Abstract

Although it is known that the in vitro MICs of rifampin and ethambutol are poorly correlated with the clinical response in Mycobacterium avium complex (MAC) lung disease (MAC-LD), evidence for this is limited. This study investigated the association between treatment outcome and the in vitro MICs of rifampin and ethambutol in patients with MAC-LD.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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