Affiliation:
1. Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA
Abstract
Dysregulation of the cell cycle underlies many human genetic diseases and cancers, yet numerous organisms, including microbes, also manipulate the cell cycle to generate both morphologic and genetic diversity as a natural mechanism to enhance their chances for survival. The eukaryotic pathogen
Cryptococcus neoformans
generates morphologically distinct polyploid titan cells critical for host adaptation and subsequent disease.
Funder
HHS | NIH | National Institute of Allergy and Infectious Diseases
HHS | NIH | National Institute of General Medical Sciences
HHS | National Institutes of Health
Publisher
American Society for Microbiology
Cited by
24 articles.
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