Recovery of a Functional Class 2 Integron from an Escherichia coli Strain Mediating a Urinary Tract Infection

Author:

Márquez Carolina12,Labbate Maurizio3,Ingold Ana J.1,Chowdhury Piklu Roy3,Ramírez Maria S.4,Centrón Daniela4,Borthagaray Graciela2,Stokes H. W.3

Affiliation:

1. Cátedra de Microbiología, Instituto de Química Biológica, Facultad de Ciencias

2. Cátedra de Microbiología, Facultad de Química, UDELAR, Montevideo, Uruguay

3. Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW 2109, Australia

4. Departmento de Microbiología, Parasitología e Immunología, Facultad de Medicina de la Universidad de Buenos Aires, Buenos Aires, Argentina

Abstract

ABSTRACT A class 2 integron was found in an Escherichia coli isolate mediating a urinary tract infection. Unlike other class 2 integrons from pathogens, the encoded IntI2 protein was functional. The integron possessed a dfrA14 cassette, and a second novel cassette in which a lipoprotein signal peptidase gene is predicted.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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