Characterization of ConE, the VirB4 Homolog of the Integrative and Conjugative Element ICE Bs1 of Bacillus subtilis

Author:

Murthy Anastasia C.1,Aleksanyan Naira1,Morton Georgeanna M.1,Toyoda Hunter C.1,Kalashyan Meri1,Chen Sirui1,Ragucci Adelyn E.12ORCID,Broulidakis Matthew P.1,Swerdlow Kyle J.1,Bui Minh N. N.1,Muccioli Maria1,Berkmen Melanie B.1ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, Suffolk University, Boston, Massachusetts, USA

2. Cancer Immunology and Virology Department, Dana Farber Cancer Institute, Boston, Massachusetts, USA

Abstract

Conjugation is a major form of horizontal gene transfer and involves the transfer of DNA from one bacterium to another through the conjugation machinery. Conjugation contributes to bacterial evolution by disseminating genes involved in antibiotic resistance, metabolism, and virulence.

Funder

National Science Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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