Influenza A Virus Uses PSMA2 for Downregulation of the NRF2-Mediated Oxidative Stress Response

Author:

Rashid Mahamud-ur12,Gao Ang2,Coombs Kevin M.123ORCID

Affiliation:

1. Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada

2. Manitoba Centre for Proteomics and Systems Biology, Winnipeg, Manitoba, Canada

3. Children’s Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada

Abstract

Influenza A virus (IAV) remains one of the most significant infectious agents, responsible for 3 million to 5 million illnesses each year and more than 50 million deaths during the 20th century. The cellular processes that promote and inhibit IAV infection and pathogenesis remain only partially understood.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

Research Manitoba

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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