Performance of Chlamydia trachomatis OmcB Enzyme-Linked Immunosorbent Assay in Serodiagnosis of Chlamydia trachomatis Infection in Women

Author:

Gupta Kanupriya1,Brown LaDraka'1,Bakshi Rakesh K.1,Press Christen G.1,Chi Xiaofei2,Gorwitz Rachel J.3,Papp John R.3,Geisler William M.1

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA

2. Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

3. Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Abstract

Chlamydia trachomatis serological assays with improved sensitivity over commercially available assays are needed to evaluate the burden of C. trachomatis infection and the effectiveness of prevention efforts. We evaluated the performance of a C. trachomatis outer membrane complex protein B (OmcB) enzyme-linked immunosorbent assay (ELISA) in the detection of anti- C. trachomatis antibody responses in C. trachomatis -infected women.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | Centers for Disease Control and Prevention

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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