Dominant-Negative Rho, Rac, and Cdc42 Facilitate the Invasion Process of Vibrio parahaemolyticus into Caco-2 Cells-Reference-Cited by-同舟云学术

Dominant-Negative Rho, Rac, and Cdc42 Facilitate the Invasion Process of Vibrio parahaemolyticus into Caco-2 Cells

Published:2002-02 Issue:2 Volume:70 Page:970-973
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Akeda Yukihiro¹,Kodama Toshio¹,Kashimoto Takashige²³,Cantarelli Vlademir¹,Horiguchi Yasuhiko²,Nagayama Kenichi¹,Iida Tetsuya¹,Honda Takeshi¹

Affiliation:

1. Department of Bacterial Infections

2. Department of Bacterial Toxinology, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871

3. Department of Veterinary Public Health, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori 034-8626, Japan

Abstract

ABSTRACT To clarify the invasive process of Vibrio parahaemolyticus , an invasion assay was performed using cells expressing dominant negative small GTPases of the Rho family. This assay showed that the dominant negative host phenotype facilitates bacterial invasion, suggesting that the mechanism of V. parahaemolyticus invasion differs from that reported for other invasive bacteria.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.70.2.970-973.2002

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