Impaired expression of interleukin 2 receptor and CD45RO antigen on lymphocytes from children with acute lymphoblastic leukemia in response to cytomegalovirus and varicella-zoster virus-Reference-Cited by-同舟云学术

Impaired expression of interleukin 2 receptor and CD45RO antigen on lymphocytes from children with acute lymphoblastic leukemia in response to cytomegalovirus and varicella-zoster virus

Published:1995-05 Issue:3 Volume:2 Page:381-384
ISSN:1071-412X
Container-title:Clinical Diagnostic Laboratory Immunology
language:en
Short-container-title:Clin Diagn Lab Immunol

Author:

Mizutani K¹,Ito M¹,Nakano T¹,Kamiya H¹,Sakurai M¹

Affiliation:

1. Department of Pediatrics, Mie University School of Medicine, Japan.

Abstract

The expression of CD25 and CD45RO in lymphocytes from patients with acute lymphoblastic leukemia in response to cytomegalovirus and varicella-zoster virus antigens was analyzed by flow cytometry. It is suggested that the defects in the immune response to cytomegalovirus and varicella-zoster virus in patients with acute lymphoblastic leukemia on chemotherapy are in the expression of CD25 and in the switching of CD45RA cells to CD45RO cells.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/cdli.2.3.381-384.1995

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