Comparison of Campylobacter jejuni Isolates Implicated in Guillain-Barré Syndrome and Strains That Cause Enteritis by a DNA Microarray

Author:

Leonard Edward E.12,Tompkins Lucy S.12,Falkow Stanley1,Nachamkin Irving3

Affiliation:

1. Department of Microbiology and Immunology

2. Division of Infectious Diseases, Stanford University, Stanford, California 94305

3. Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104

Abstract

ABSTRACT We asked whether Campylobacter jejuni isolated from patients with Guillain-Barré syndrome (GBS) differ from isolates isolated from patients with uncomplicated gastrointestinal infection using DNA microarray analysis. We found that specific GBS genes or regions were not identified, and microarray analysis confirmed significant genomic heterogeneity among the isolates.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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